Dani Pedrosa crashed while leading on lap 4, while Valentino Rossi crashed from a close second behind team-mate Jorge Lorenzo on lap 10 of 28.
Third in the championship Casey Stoner has withdrawn until Estoril on October 4 to try and return to full fitness.
Stoner’s place at Ducati Marlboro has been taken by Mika Kallio, whose Pramac ride has been handed to Aleix Espargaro for Indianapolis and Misano. 20-year-old Espargaro made his MotoGP debut this weekend.
1. Jorge Lorenzo SPA Fiat Yamaha Team 47min 13.592 sec
2. Alex de Angelis RSM San Carlo Honda Gresini 47min 23.027 sec
3. Nicky Hayden USA Ducati Marlboro Team 47min 26.539 sec
4. Andrea Dovizioso ITA Repsol Honda Team 47min 27.070 sec
5. Colin Edwards USA Monster Yamaha Tech 3 47min 39.846 sec
6. James Toseland GBR Monster Yamaha Tech 3 47min 46.000 sec
7. Loris Capirossi ITA Rizla Suzuki MotoGP 47min 47.992 sec
8. Mika Kallio FIN Ducati Marlboro Team 47min 48.448 sec
9. Toni Elias SPA San Carlo Honda Gresini 47min 58.597 sec
10. Dani Pedrosa SPA Repsol Honda Team 47min 58.969 sec
11. Chris Vermeulen AUS Rizla Suzuki MotoGP 47min 59.070 sec
12. Randy de Puniet FRA LCR Honda MotoGP 48min 5.886 sec
13. Aleix Espargaro SPA Pramac Racing 48min 17.144 sec
14. Gabor Talmacsi HUN Scot Racing Team MotoGP 48min 28.678 sec
2. Alex de Angelis RSM San Carlo Honda Gresini 47min 23.027 sec
3. Nicky Hayden USA Ducati Marlboro Team 47min 26.539 sec
4. Andrea Dovizioso ITA Repsol Honda Team 47min 27.070 sec
5. Colin Edwards USA Monster Yamaha Tech 3 47min 39.846 sec
6. James Toseland GBR Monster Yamaha Tech 3 47min 46.000 sec
7. Loris Capirossi ITA Rizla Suzuki MotoGP 47min 47.992 sec
8. Mika Kallio FIN Ducati Marlboro Team 47min 48.448 sec
9. Toni Elias SPA San Carlo Honda Gresini 47min 58.597 sec
10. Dani Pedrosa SPA Repsol Honda Team 47min 58.969 sec
11. Chris Vermeulen AUS Rizla Suzuki MotoGP 47min 59.070 sec
12. Randy de Puniet FRA LCR Honda MotoGP 48min 5.886 sec
13. Aleix Espargaro SPA Pramac Racing 48min 17.144 sec
14. Gabor Talmacsi HUN Scot Racing Team MotoGP 48min 28.678 sec
DNF:
Valentino Rossi ITA Fiat Yamaha Team
Niccolo Canepa ITA Pramac Racing
Marco Melandri ITA Hayate Racing Team
Valentino Rossi ITA Fiat Yamaha Team
Niccolo Canepa ITA Pramac Racing
Marco Melandri ITA Hayate Racing Team